Introduction

The bgcorrect node is used to perform background correction on the microarray data.

The methods used in background correction is based on the assumption that the background effect is additive, i.e. the observed signal is a sum of a background signal and a true signal, $ S=N+T$. This assumption is a simplification, hence it is believed that to do background correction on arrays introduces noise instead of removing it. Better routines, and technology in microarray experiments leads to less noisy data, and this maybe removes the need for background correction [2].



Bjørn Kåre Alsberg 2006-04-06