scale

The scale normalisation method was proposed by [8,9] and is further explained by [3]. The idea is simply to scale the log-ratios to have the same median-absolute-deviation (MAD) across arrays. The MAD score for array $ i$ is given by

$\displaystyle MAD_i=$median$\displaystyle _j \{ \vert M_{ij}-$median$\displaystyle _j(M_{ij})\vert \},$    

where $ M_{ij}$ is the $ j$th log-ratio in the $ i$th print group.

Bjørn Kåre Alsberg 2006-04-06